The impact of amyloid-β or tau on cognitive change in the presence of severe cerebrovascular disease

…, Alzheimer's Disease Neuroimaging … - … Disease, 2020 - content.iospress.com
… We included 60 subcortical vascular cognitive impairment (… AD (remaining 121 subjects
with clinically normal cognition) … , the effects of Aβ positivity or tau burden on cognitive decline

Influence of comorbidity of cerebrovascular disease and amyloid-β on Alzheimer's disease

N Yassi, S Hilal, Y Xia, YY Lim… - … Disease, 2020 - content.iospress.com
… to measuring cerebrovascular disease burden, such as the … of our analyses may be subject
to inherent challenges with … of limiting the impact of cerebrovascular disease on cognition. …

Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients

H Jang, HJ Kim, S Park, YH Park, Y Choe… - European journal of …, 2020 - Springer
… Aβ-positive (Aβ+) individuals could be grouped into the following … CSVD burden may have
an effect on cognitive impairment … Finally, we investigated the trajectories in cognition and MRI …

Brain amyloid β, cerebral small vessel disease, and cognition: A memory clinic study

…, S Hilal, SG Villaraza, A Reilhac, B Gyanwali… - Neurology, 2020 - AAN Enterprises
… to individuals with subcortical vascular cognitive impairment. … although individuals with MCI
or AD had higher brain Aβ burden … MCI and AD with and without cerebrovascular disease. …

Independent effects of amyloid and vascular markers on long‐term functional outcomes: An 8‐year longitudinal study of subcortical vascular cognitive impairment

SH Kang, S Woo, S Kim, JP Kim, H Jang… - European Journal of …, 2022 - Wiley Online Library
individuals without dementia [32]. Therefore, it would be reasonable to expect that the effects
of … All participants in our SVCI cohort had severe CSVD burdens, which makes it difficult to …

Comorbid amyloid with cerebrovascular disease in domain-specific cognitive and neuropsychiatric disturbances: a cross-sectional memory clinic study

CN Kan, X Huang, L Zhang, S Hilal, A Reilhac… - Neurobiology of …, 2023 - Elsevier
… These potentially additive effects of Aβ and CeVD burden … unexplored in individuals with
normal cognition or MCI. … domain-specific cognitive impairment and NPS syndromes of positron …

Amyloid positivity in the Alzheimer/subcortical-vascular spectrum

SH Kang, ME Kim, H Jang, H Kwon, H Lee, HJ Kim… - Neurology, 2021 - AAN Enterprises
… , we enrolled individuals with Alzheimer/subcortical-vascular … or signs suggestive of
cerebrovascular disease, whereas in the … with CSVD as well as Aβ burden, 38,39 which may …

White matter abnormalities are key components of cerebrovascular disease impacting cognitive decline

P Vemuri, J Graff-Radford, TG Lesnick… - Brain …, 2021 - academic.oup.com
… 1089 individuals aged ≥60 years with concurrent amyloid-PET … Subcortical/cortical infarctions
and lobar/deep CMBs might … impact of PC3 would be on baseline cognition and not rate of …

Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction

SH Kang, M Kang, JH Han, ES Lee, KJ Lee… - Alzheimer's Research & …, 2023 - Springer
… compare the clinical characteristics of the post-stroke normal cognition (PSNC) and PSCI
groups. … infarctions might be higher than that in normal elderly individuals. Several mechanisms …

Frequency and underlying pathology of pure vascular cognitive impairment

S Oveisgharan, RJ Dawe, L Yu, A Kapasi… - JAMA …, 2022 - jamanetwork.com
individuals without neurodegenerative pathologies and determine the extent to which
cerebrovascular disease … driving pathology is AD, which is unrelated to the burden of vascular risk …